Grid + Flex Layout

With body display: grid + main display: flex.

Main Content

HTML5 Semantic Structure

body {
    min-height: 100vh;
    display: grid;
    grid-template-rows: auto 1fr auto;
}
body>*>div {
    max-width: 100ch;
    margin: 0 auto;
}
main>div {
    display: flex;
    flex-wrap: wrap;
}
main>div>aside {
    flex: 1 1 10em;
}
main>div>section {
    flex: 4 1 30em;
}